Figure 3.

Administration of sNgR-Fc improves neurological function in rats after PCI.

(A) Escape latency after treatment with PBS or sNgR-Fc in rats with PCI at various time points. (B) Travelled distance following treatment with PBS or sNgR-Fc in rats with PCI at the indicated time points. (C) Distance traveled in the target quadrant in the PBS and sNgR-Fc groups. (D) Total time spent in passing through the former platform location in the PBS and sNgR-Fc groups. (E) Neurological severity score in the PBS and sNgR-Fc groups. All data are expressed as the mean ± SD (n = 6; Student’s t-test). *P < 0.05, vs. PBS group. sNgR-Fc: Soluble Nogo66 receptor-Fc protein; PBS: phosphate-buffered saline.