Table 1.
Descriptive Statistics of Demographic Data for Subjects Included in the Pharmacokinetic Population
| PK Population | ||||
|---|---|---|---|---|
| Category | Comparison (A/C), n = 34 | Comparison (B/A), n = 32 | Comparison (B/C), n = 31 | |
| Age (years) | Mean ± SD | 35 ± 9 | 36 ± 9 | 36 ± 9 |
| Range | 23–50 | 23–50 | 23–50 | |
| Median | 35 | 35 | 35 | |
| BMI (kg/m2) | Mean ± SD | 24.62 ± 3.01 | 24.51 ± 3.11 | 24.35 ± 3.02 |
| Range | 19.54–29.93 | 19.54–29.93 | 19.54–29.93 | |
| Median | 24.44 | 23.92 | 23.69 | |
| Height (cm) | Mean ± SD | 168.8 ± 7.8 | 168.6 ± 7.6 | 168.5 ± 7.6 |
| Range | 156.5–186.0 | 156.5–186.0 | 156.5–186.0 | |
| Median | 166.3 | 166.3 | 165.5 | |
| Weight (kg) | Mean ± SD | 70.49 ± 12.27 | 70.02 ± 12.26 | 69.43 ± 11.98 |
| Range | 52.70–103.20 | 52.70–103.20 | 52.70–103.20 | |
| Median | 71.10 | 70.50 | 70.50 | |
PK, pharmacokinetic; n, number of observations; SD, standard deviation; BMI, body mass index.
A: levothyroxine sodium oral solution administered with water.
B: levothyroxine sodium oral solution administered without water.
C: levothyroxine sodium capsule.