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. 2018 Aug 28;8(4):521–528. doi: 10.1002/cpdd.608

Table 2.

Summary of Pharmacokinetic Parameters for Baseline‐Corrected Serum Levothyroxine for Each Treatment

Levothyroxine Sodium Oral Solution With Water (A) Levothyroxine Sodium Oral Solution Without Water (B) Levothyroxine Sodium Capsule (C)
n 35 32 34
AUC0–48 a 1739.26 ± 438.25 1755.86 ± 330.86 1764.14 ± 380.88
(ng·h/mL) (25.20) (18.84) (21.59)
Cmax a 72.66 ± 16.67 71.30 ± 14.19 76.64 ± 16.48
(ng/mL) (22.95) (19.91) (21.51)
Tmax b 1.50 2.50 2.00
(h) (1.00–4.00) (1.00–5.00) (1.00–4.00)
a

Mean ± SD (CV%).

b

Median (Min‐Max).