Table 2.
Comparison of baseline characteristics of patients with decompensated cirrhosis with vs without further decompensation
| Decompensated cirrhosis patients, n = 138 | No further hepatic decompensation, n = 92 | Further hepatic decompensation, n = 46 | P‐value | |
|---|---|---|---|---|
| Sex, male/female (% male) | 86/54 (62) | 57/35 (62) | 27/19 (59) | 0.711 |
| Age, yr | 54 ± 12 | 53 ± 12 | 54 ± 13 | 0.808 |
| BMI, kg/m2 | 25 ± 5 | 25 ± 5 | 24 ± 5 | 0.771 |
| Aetiology | ||||
| Virus hepatitis, n (%) | 33 (24) | 20 (22) | 13 (28) | 0.738 |
| (N)AFLD, n (%) | 72 (52) | 51 (55) | 21 (46) | |
| Other, n (%) | 17 (12) | 11 (12) | 6 (13) | |
| Cryptogenic, n (%) | 16 (12) | 10 (11) | 6 (13) | |
| Diabetes, n (%) | 23 (17) | 16 (17) | 7 (15) | 0.747 |
| Fasting glucose, mg/dL | 101 ± 21 | 99 ± 18 | 122 ± 53 | 0.662 |
| Triglycerides, mg/dL | 91 ± 49 | 90 ± 48 | 94 ± 52 | 0.667 |
| Total cholesterol mg/dL | 151 ± 54 | 151 ± 52 | 150 ± 57 | 0.870 |
| Statin treatment, n (%) | 8 (6) | 5 (5) | 3 (7) | 0.350 |
| History of variceal bleeding, n (%) | 43 (31) | 24 (26) | 19 (41) | 0.069 |
| History of or current ascites | ||||
| No ascites | 29 (21) | 22 (24) | 7 (15) | 0.422 |
| Mild/moderate (%) | 87 (63) | 57 (62) | 30 (65) | |
| Severe, n (%) | 22 (16) | 13 (14) | 9 (20) | |
| History of or current hepatic encephalopathy, n (%) | 45 (33) | 24 (26) | 21 (46) | 0.021 |
| INR | 1.4 ± 0.3 | 1.3 ± 0.3 | 1.4 ± 0.2 | 0.298 |
| Albumin, g/L | 35 ± 6 | 35 ± 4 | 35 ± 6 | 0.624 |
| MELD‐Na score, points | 15 ± 5 | 14 ± 5 | 16 ± 5 | 0.004 |
| Liver stiffness, kPa | 46 (26‐69) | 46 (26‐70) | 46 (27‐69) | 0.895 |
| CAP, dB/m | 235 ± 66 | 238 ± 66 | 231 ± 68 | 0.575 |
| HVPG, mm Hga | 19 (15‐23) | 19 (15‐22) | 21 (17‐25) | 0.023 |
BMI, body mass index; CAP, controlled attenuation parameter; cACLD, compensated advanced chronic liver disease; HVPG, hepatic venous pressure gradient; INR, international normalized ratio; MELD‐Na, model for end‐stage liver disease including sodium; (N)AFLD, (non)alcoholic fatty liver disease.
Statistically significant P‐values are shown in bold.
a
Data were available in 103 patients (n = 70 without decompensation and n = 33 with decompensation).