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. 2018 Jul 2;8(3):304–313. doi: 10.1002/cpdd.597

Table 2.

Kremezin/Roxadustat DDI Study Treatment Schedule (Part 2)

Sequence Period 1 Period 2 Period 3
E (n = 3) Kremezin concomitant 2 hours before roxadustat Roxadustat alone Kremezin concomitant 2 hours after roxadustat
F (n = 3) Kremezin concomitant 2 hours before roxadustat Kremezin concomitant 2 hours after roxadustat Roxadustat alone
G (n = 3) Roxadustat alone Kremezin concomitant 2 hours before roxadustat Kremezin concomitant 2 hours after roxadustat
H (n = 3) Roxadustat alone Kremezin concomitant 2 hours after roxadustat Kremezin concomitant 2 hours before roxadustat
I (n = 3) Kremezin concomitant 2 hours after roxadustat Kremezin concomitant 2 hours before roxadustat Roxadustat alone
J (n = 3) Kremezin concomitant 2 hours after roxadustat Roxadustat alone Kremezin concomitant 2 hours before roxadustat

DDI, drug‐drug interaction.