Skip to main content
. 2018 Sep 27;31(6):e12656. doi: 10.1111/dth.12656

Table 1.

Characteristics, treatments, and outcomes of patients with lichen planopilaris treated with oral tofacitinib

Patient # Sex Disease duration (years) Type/biopsy proven Prior treatmentsattempted Daily tofacitinib dose (mg) Treatment duration (months) Concurrent therapies
1 M 6 Patchy Topical steroids, intralesional triamcinolone, minoxidil, excimer laser, hydroxychloroquine, pioglitazone, prednisone 15 10 Intralesional triamcinolone
2 M 15 Patchy Pioglitazone, mycophenolic acid 10 17
3 M 1 Diffuse/yes Topical steroids, intralesional triamcinolone, doxycycline, excimer laser, prednisone, hydroxychloroquine, pioglitazone, finasteride 10 3
4 F 2 FFA Topical steroids, intralesional triamcinolone, doxycycline, hydroxychloroquine 10 9 Intralesional triamcinolone
5 F 1 FFA/yes Topical steroids, minoxidil, excimer laser, doxycycline, hydroxychloroquine, finasteride 10 6 Intralesional triamcinolone, hydroxychloroquine
6 F 10 Patchy Topical steroids, minocycline, finasteride 10 7 Tacrolimus ointment, intralesional triamcinolone
7 F 2 Patchy Intralesional triamcinolone 15 19
8 M 1 Patchy/yes Topical steroids, doxycycline, hydroxychloroquine, pioglitazone, finasteride, mycophenolic acid 10 16 Hydroxychloroquine
9 F 1 Patchy/yes Intralesional triamcinolone, doxycycline, finasteride 10 10
10 F 2 Diffuse/yes Topical steroids, doxycycline 10 2
Patient # LPPAI pre‐treatment LPPAI post‐treatment % changeLPPAI Notes
1 5.33 1.42 −73
2 5.58 1.75 −68
3 7.5 7.5 0 No improvement
4 6.67 4.58 −32
5 5.667 0.333 −94
6 Not assessed No improvement
7 Not assessed Flared after stoppingtofacitinib
8 6.67 2.08 −69
9 6 4.25 −30
10 6.33 2.75 −5

Abbreviation: LPPAI = lichen planopilaris activity index.