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. 2018 Jul 13;19(2):475–487. doi: 10.1111/ajt.14970

Table 2.

Detailed demographic, clinical, and transplant‐associated patient findings

No. Sex Reason for HSCT Donor HLA mismatch Cause of ESRD Age (y) IS after RT IS‐free (y)
At RT Donor
1 M Wiskott‐Aldrich Syndrome Mother Two mismatches Mesangial proliferative GN 18 42 Glucocorticoids, CyA 24
2 F ALL Brother HLA‐identical HUS 28 25 None, later AZA and Glucocorticoids 0
3 F Aplastic anemia Father Three mismatches Radiation nephritis 14 NK Glucocorticoids, CyA 21
4 F CML Sister Two mismatches BMT‐NP 37 35 None 19
5 F AML Brother HLA‐identical HUS 40 NK Glucocorticoids and AZA NK
6 M AML Sister HLA‐identical BMT‐NP 39 33 None 10
7 M Morbus Hodgkin Brother HLA‐identical BMT‐NP 48 51 None 4
8 F AML Unrelated HLA‐identical BMT‐NP 29 NK None 9
9 F CML Sister HLA‐identical Diabetes type 1 37 NK None 17
10 M CML Sister HLA‐identical Unknown 64 56 None 11
11 M Lymphoma Sibling HLA‐identical HUS/TTP 59 67 MMF, Glucocorticoids 5
12 F ALL Mother One mismatch BMT‐NP 30 57 MMF, Glucocorticoids 5
13 M AML Father Two mismatches CNI‐associated 21 45 Tac, MMF, Glucocorticoids 9
14 M AML Sister HLA‐identical TTP 28 26 Tac, MMF 3
15 F Comb. immune‐deficiency syndrome Mother Three mismatches Loss of first renal allograft due to infection 22 61 CyA, Glucocorticoids 6
16 M Idiopathic aplastic anemia Sister HLA‐identical Chronic nephangiosclerosis 41 52 Glucocorticoids 9
17 F AML Unrelated HLA‐identical Complication of aGvHD treatment 17 46 Tac, Glucocorticoids 9
18 M Polymorphic rhabdomyosarkoma Father Two mismatches BMT‐NP 21 43 Glucocorticoids 3
19 M ALL Father Three mismatches BMT‐NP 25 46 Glucocorticoids 1
20 M B‐cell non‐Hodgkin lymphoma Sister HLA‐identical Acute and chronic rejection of 1. transplant kidney 30 22 Glucocorticoids 13
21 M Aplastic anemia Sister HLA‐identical CNI toxicity 54 63 Single Dose Glucocorticoid 1,5
22 F Sickle cell disease Mother Three mismatches Focal segmental glomerulosclerosis due to SCD 28 56 Glucocorticoid, MMF, Tacrolimus 0,2

By some authors the cause of ESRD was described as bone marrow transplant nephropathy (BMT‐NP). In the literature BMT‐NP is defined as chronic renal disease presenting within 100 days after BMT. It includes chemo‐irradiation–associated nephropathies caused by the conditioning therapies in the absences of other nephrotoxins.14, 40