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. 2019 Jun 17;7:e7116. doi: 10.7717/peerj.7116

Table 1. Top 10 most-cited articles about immunotherapy of sepsis.

Title Publication year Journals (citescore 2017) First author Country Scopus citations
Surviving sepsis campaign: International guidelines for management of severe sepsis and septic shock: 2012 2013 Critical Care Medicine (3.24) Dellinger, Richard Phillip US 3,435
The third international consensus definitions for sepsis and septic shock (sepsis-3) 2016 JAMA (7.30) Singer, Mervyn UK 2,859
The pathophysiology and treatment of sepsis 2003 New England Journal of Medicine (14.75) Hotchkiss, Richard S. US 2,711
Surviving sepsis campaign: International guidelines for management of severe sepsis and septic shock, 2012 2013 Intensive Care Medicine (3.99) Dellinger, Richard Phillip US 2,409
Recombinant Human Interleukin 1 Receptor Antagonist in the Treatment of Patients With Sepsis Syndrome: Results From a Randomized, Double-blind, Placebo-Controlled Trial 1994 JAMA (7.30) Fisher, Charles J. US 842
Immunosuppression in patients who die of sepsis and multiple organ failure 2011 JAMA (7.30) Boomer, Jonathan S. US 666
Novel strategies for the treatment of sepsis 2003 Nature Medicine (16.81) Riedemann, Niels Christoph Germany 635
Sepsis-induced immunosuppression: From cellular dysfunctions to immunotherapy 2013 Nature Reviews Immunology (17.43) Hotchkiss, Richard S. US 593
A Controlled Clinical Trial of E5 Murine Monoclonal IgM Antibody to Endotoxin in the Treatment of Gram-Negative Sepsis 1991 JAMA (7.30) Greenman, Richard L. US 583
Confirmatory interleukin-1 receptor antagonist trial in severe sepsis: A phase III, randomized, double-blind, placebo-controlled, multicenter trial 1997 Critical Care Medicine (3.24) Opal, Steven M. US 553