Table 1. Differential expression levels of traditional tumor markers in plasma of GC, Pre and health controls.
| GC | Pre | Pre vs NC | NC | GC vs NC | ||||
|---|---|---|---|---|---|---|---|---|
| n | mean ± SD | n | mean ± SD | pvalue | n | mean ± SD | pvalue | |
| AFP | 85 | (26.14 ± 133.56) | 66 | (3.32 ± 1.72) | 0.0505 | 45 | (3.69 ± 1.25) | 0.3002 |
| CEA | 85 | (32.23 ± 128.76) | 66 | (1.82 ± 1.39) | 0.3122a | 45 | (2.08 ± 1.20) | 0.0011 |
| Ferritin | 80 | (281.08 ± 383.42) | 61 | (270.11 ± 302.39) | 0.1270a | 45 | (185.67 ± 237.46) | 0.9908 |
| CA125 | 68 | (59.22 ± 92.72) | 53 | (12.50 ± 7.78) | 0.9363 | 45 | (11.07 ± 4.05) | 0.0091 |
| CA153 | 67 | (13.44 ± 17.70) | 50 | (10.41 ± 5.45) | 0.0065a | 45 | (13.67 ± 5.83) | 0.0049 |
| CA199 | 83 | (107.03 ± 251.90) | 57 | (13.95 ± 12.37) | 0.1071 | 45 | (14.58 ± 8.22) | 0.0705 |
| CA211 | 62 | (16.15 ± 44.84) | 40 | (2.96 ± 1.40) | <0.0001 | 45 | (2.09 ± 0.48) | 0.0002 |
| CA242 | 66 | (19.17 ± 39.24) | 45 | (4.92 ± 4.8) | 0.2976a | 36 | (6.14 ± 5.48) | 0.1425 |
| CA50 | 77 | (38.01 ± 99.02) | 48 | (8.18 ± 5.97) | 0.0101a | 34 | (4.91 ± 4.46) | 0.0089 |
| CA724 | 75 | (15.12 ± 38.23) | 44 | (2.49 ± 2.87) | 0.2347a | 26 | (3.32 ± 2.59) | 0.2049 |
Notes.
a
For these categorical variables, the p value were calculated by Student’s t-test. Mann–Whitney U test was used to determine other categorical variables with statistical significance at the level of p < 0.05.