Table 1. Demographic and clinical characteristics of ESRD and control group.
| Variables | ESRD (N = 77) | HC (N = 30) | P-value |
|---|---|---|---|
| Age (year) | 59 ± 13.9 | 59.3 ± 6.8 | 0.956 |
| Sex (M/F) | 77 (43/34) | 30 (17/13) | 0.939 |
| BMI (kg/m2) | 23 ± 3.2 | 22.1 ± 1.5 | 0.091 |
| PTH (pg/mL) | 246.7 ± 47.9 | – | – |
| CREA (μmol/L) | 905 ± 268.9a | 65.4 ± 14.7 | <0.001 |
| BUN (mmol/L) | 22.6 ± 6.2a | 5.2 ± 1.1 | <0.001 |
| UA (μmol/L) | 444.9 ± 110.8a | 284.3 ± 66.7 | <0.001 |
| Ca (mmol/L) | 2.2 ± 0.2a | 2.4 ± 0.2 | <0.001 |
| P (mmol/L) | 1.8 ± 0.5a | 1.0 ± 0.1 | <0.001 |
| TG (mmol/L) | 1.9 ± 1.1a | 1.1 ± 0.5 | <0.001 |
| CHOL (mmol/L) | 3.5 ± 1.0a | 4.7 ± 0.5 | <0.001 |
| HDL-C (mmol/L) | 1.0 ± 0.4a | 1.5 ± 0.3 | <0.001 |
| LDL-C (mmol/L) | 1.7 ± 0.7a | 2.8 ± 0.5 | <0.001 |
| WBC (109/L) | 5.7 ± 1.7 | 5.4 ± 1.3 | 0.416 |
| HGB (g/L) | 106 ± 17.2a | 140 ± 19 | <0.001 |
| PLT (109/L) | 151 ± 62.6a | 193.7 ± 50.6 | 0.003 |
| GLU (mmol/L) | 6.1 ± 2.8 | 5.4 ± 0.9 | 0.061 |
| ALB (g/L) | 38.3 ± 4.0a | 44.8 ± 3.0 | <0.001 |
| AST (U/L) | 20 ± 16.3 | 18.1 ± 7.5 | 0.548 |
| ALT (U/L) | 13.4 ± 8.3 | 15.7 ± 6.3 | 0.190 |
| ALP (U/L) | 96.2 ± 47.2 | 92.2 ± 28.8 | 0.675 |
| TBIL (μmol/L) | 6.9 ± 2.8 | 7.3 ± 2.3 | 0.459 |
| DBIL (μmol/L) | 3.3 ± 1.5 | 3.3 ± 1.9 | 0.920 |
| TBA (ng/mL) | 3,151.4 ± 270.0a | 1,849.2 ± 269.8 | 0.001 |
Notes:
Data represent means ± SD or means ± SEM. Comparisons performed via t-test (ESRD vs. HC).
a
P < 0.05.