Table 2. Effect of icariside II on SOD, GSH-Px, catalase and MDA levels in brain tissue.
Group | SOD (U/mg) | GSH-Px (U/mg) | Catalase (U/mg) | MDA (nmol/mg) |
---|---|---|---|---|
Sham-operated | 16.29±2.44 | 18.55±3.45 | 5.12±1.12 | 4.58±1.05 |
Model | 8.95±2.02* | 10.67±2.73* | 2.27±0.34* | 8.48±1.77* |
5 mg/kg icariside II | 9.34±2.15* | 11.38±2.42* | 2.58±0.47* | 7.05±1.43*# |
10 mg/kg icariside II | 10.03±2.34* | 12.31±2.83*# | 3.17±0.59*# | 6.33±1.31*#$ |
20 mg/kg icariside II | 12.27±2.63*#$ | 14.39±2.94*#$ | 4.21±0.49*#$※ | 5.74±1.09*#$※ |
Values are mean±SD. *P < 0.05 vs sham-operated group; #P < 0.05 vs model group; $P < 0.05 vs 5 mg/kg icariside II group; ※P < 0.05 vs 10 mg/kg icariside II group. SOD, superoxide dismutase; GSH-Px, glutathione peroxidase; MDA, malondialdehyde.