Table 3. Effect of icariside II on Nrf2 and HO-1 protein expressions in brain tissue.
Group | Nrf2/β-actin | HO-1/β-actin |
---|---|---|
Sham-operated | 0.98±0.22 | 0.68±0.19 |
Model | 1.52±0.29* | 1.34±0.25* |
5 mg/kg icariside II | 1.94±0.27*# | 1.46±0.29* |
10 mg/kg icariside II | 2.34±0.36*#$ | 1.95±0.34*#$ |
20 mg/kg icariside II | 2.84±0.44*#$※ | 2.58±0.41*#$※ |
Values are mean±SD. *P < 0.05 vs sham-operated group; #P < 0.05 vs model group; $P < 0.05 vs 5 mg/kg icariside II group; ※P < 0.05 vs 10 mg/kg icariside II group.