Figure 1. Histologic injury of intestinal mucosa and lung (hematoxylin and eosin staining. magnification ×200) and the evaluation of damages with Chiu’s scores and lung injury scores and wet/dry weight ratios of intestinal and lung tissues. (A) Representative images of intestine and lung. In the Sham group mucosal was normal. In the II/R group, significantly severe intestinal injury was seen. Compare with the II/R group, the damage of intestine in the P group was mitigated remarkably. Whereas, in the W group, histologic injury in intestine aggravated compared with the P group. Normal lung tissue was seen in the Sham group. In contrast, seriously lung injury was observed in the II/R group. But compare with the II/R group, the damage of lung was slighter in the P group. However, wortmannin deteriorated the result, alveolar wall thickening, inflammatory cells accumulation, severe alveolar septal congestion, edema and hemorrhage were found in the W group. (B) The determination of Chiu’s scores and lung injury scores and wet/dry weight ratios of intestinal and lung tissues. The data are expressed as mean values ± standard deviation (n=6). *P<0.05 vs. Sham group. ^# P<0.05 vs. II/R group. ^★ P <0.05 vs. P group.