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Least Squares Means and Ratios of AUC0‐t and Cmax for Cyclosporine Before (Day 6) and After a Single Dose of Amenamevir (n = 24)
| LS Means | ||||
|---|---|---|---|---|
| Cyclosporine (Day 6) | Amenamevir With Cyclosporine (Day 7) | Ratio (%) Day 7/Day 6 | 90%CI | |
| Cmax (μg/mL) | 480 | 462 | 96 | 92, 101 |
| AUC0‐τ (ng ⋅ h/mL) | 1931 | 1960 | 102 | 99, 105 |
AUC0–τ, area under concentration‐time curve over the dosing interval; CI, confidence interval; Cmax, peak concentration; LS, least squares.
