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Time course of changes in transmission electron microscopy images during in vitro chondrogenesis of synovial MSCs cultured with or without petaloid RCP. An initial 125k synovial MSCs were cultured with or without petaloid RCP in chondrogenic medium for 1, 7, and 21 days. White arrowheads indicate petaloid RCP. “+” indicates an empty space. Asterisks indicate collagen fibrils.
