Table 3.
Patient ID | Sex | Age | BMI | Previous Revision | Months Between Implantation of Previous TEP and | Systemic Antibiotic Therapy Within 48 h After | ||
---|---|---|---|---|---|---|---|---|
Explantation of TEP | Incipient complaints | Spacer Implantation | Spacer Explantation | |||||
H1a | M | 73 | 21 | No | 21 | 17 | Ce 3 × 1500 mg/d; Mo 1 × 400 mg/d | Ce 3 × 1500 mg/d; Mo 1 × 400 mg/d |
H2b | M | 68 | 22 | Yesc | 14 | 4 | Ri 2 × 600 mg/d; Va 2 × 1000 mg/d | Ri 2 × 600 mg/d; Va 2 × 1000 mg/d |
H3 | M | 59 | 32 | No | 172 | 169 | Ce 3 × 1500 mg/d | Ce 3 × 1500 mg/d |
H4b | F | 79 | 29 | Yesd | 123 | 117 | Ce 3 × 1500 mg/d; Le 1 × 500 mg/d | Ri 1 × 600 mg/d; Va 2 × 1000 mg/d |
H5a | M | 55 | 33 | No | 179 | 178 | Ri 1 × 600 mg/d; Le 1 × 500 mg/d | Ri 2 × 600 mg/d; Le 2 × 500 mg/d |
H6 | M | 77 | 29 | No | 72 | 57 | Cl 2 × 600 mg/d | Le 2 × 500 mg/d |
H7 | F | 78 | 19 | No | 40 | 23 | Ce 3 × 1500 mg/d; Mo 1 × 400 mg/d | Ce 3 × 1500 mg/d; Le 2 × 500 mg/d |
H8b | M | 58 | 34 | No | 75 | 74 | Ri 2 × 600 mg/d; Va 2 × 1000 mg/d; | Ce 3 × 1500 mg/d; Le 2 × 500 mg/d |
H9 | M | 75 | 32 | No | 1 | 0 | Ce 3 × 1500 mg/d; Mo 1 × 400 mg/d | Cl 2 × 600 mg/d; Le 2 × 500 mg/d |
H10 | M | 66 | 34 | No | 98 | 61 | Ce 3 × 1500 mg/d; Le 1 × 500 mg/d | Cl 3 × 600 mg/d; Le 2 × 500 mg/d |
K1a | F | 49 | 34 | Yesd | 133 | 118 | Ce 3 × 1500 mg/d; Mo 1 × 400 mg/d | Cl 3 × 600 mg/d; |
K2a | F | 56 | 39 | Yesd | 7 | 1 | Ce 3 × 1500 mg/d; Cl 2 × 600 mg/d | Ce 3 × 1500 mg/d; Cl 2 × 600 mg/d |
K3 | F | 55 | 30 | Yesd | 52 | 52 | Ce 3 × 1500 mg/d; Le 2 × 500 mg/d | Ce 3 × 1500 mg/d; Le 2 × 500 mg/d |
K4 | M | 75 | 37 | No | 95 | 81 | Ce 3 × 1500 mg/d; Mo 1 × 400 mg/d | Ce 3 × 1500 mg/d; Mo 1 × 400 mg/d |
K5 | F | 73 | 27 | No | 178 | 176 | Cl 2 × 600 mg/d | Ce 3 × 1500 mg/d |
K6 | F | 75 | 27 | Yesd | 29 | 26 | Ce 3 × 1500 mg/d; Mo 1 × 400 mg/d | Ce 3 × 1500 mg/d; Le 2 × 500 mg/d |
K7 | F | 73 | 31 | Yesd | 8 | 8 | Ce 3 × 1500 mg/d; Le 2 × 500 mg/d | Ce 3 × 1500 mg/d |
K8 | F | 73 | 37 | Yesc | 78 | 77 | Ri 1 × 600 mg/d; Le 1 × 500 mg/d; Fl 4 × 2000 mg/d | Cl 3 × 600 mg/d; Le 2 × 500 mg/d |
Mean/total | 9 M/9 F | 67.1 ± 9.4 | 30.4 ± 5.4 | 8 | 76.4 ± 58.9 | 68.8 ± 59.1 |
Cumulative data of all patients are either presented as mean ± SD or total number.
H = hip patient; K = knee patient; Antibiotics: Ce = Cefuroxim, Cl = Clindamycin, Fl = Flucloxacillin, Le = Levofloxacin, Mo = Moxifloxacin, Ri = Rifampicin, Va = Vancomycin, all systemic antibiotic treatment within the first 48 h after operation was administered intravenously.
Patient excluded from analysis of wound exudate due to missing sample at spacer explantation.
Patient excluded from analysis of vancomycin release due to systemic antibiotics therapy with vancomycin at time point of sample collection.
Wound revisions and debridements.
Partial or total component exchange surgery.