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. 2018 Oct 12;107(5):1587–1597. doi: 10.1002/jbm.b.34251

Table 3.

Patient Details and Systemic Antibiotic Therapy at the Time Point of Sample Collection

Patient ID Sex Age BMI Previous Revision Months Between Implantation of Previous TEP and Systemic Antibiotic Therapy Within 48 h After
Explantation of TEP Incipient complaints Spacer Implantation Spacer Explantation
H1a M 73 21 No 21 17 Ce 3 × 1500 mg/d; Mo 1 × 400 mg/d Ce 3 × 1500 mg/d; Mo 1 × 400 mg/d
H2b M 68 22 Yesc 14 4 Ri 2 × 600 mg/d; Va 2 × 1000 mg/d Ri 2 × 600 mg/d; Va 2 × 1000 mg/d
H3 M 59 32 No 172 169 Ce 3 × 1500 mg/d Ce 3 × 1500 mg/d
H4b F 79 29 Yesd 123 117 Ce 3 × 1500 mg/d; Le 1 × 500 mg/d Ri 1 × 600 mg/d; Va 2 × 1000 mg/d
H5a M 55 33 No 179 178 Ri 1 × 600 mg/d; Le 1 × 500 mg/d Ri 2 × 600 mg/d; Le 2 × 500 mg/d
H6 M 77 29 No 72 57 Cl 2 × 600 mg/d Le 2 × 500 mg/d
H7 F 78 19 No 40 23 Ce 3 × 1500 mg/d; Mo 1 × 400 mg/d Ce 3 × 1500 mg/d; Le 2 × 500 mg/d
H8b M 58 34 No 75 74 Ri 2 × 600 mg/d; Va 2 × 1000 mg/d; Ce 3 × 1500 mg/d; Le 2 × 500 mg/d
H9 M 75 32 No 1 0 Ce 3 × 1500 mg/d; Mo 1 × 400 mg/d Cl 2 × 600 mg/d; Le 2 × 500 mg/d
H10 M 66 34 No 98 61 Ce 3 × 1500 mg/d; Le 1 × 500 mg/d Cl 3 × 600 mg/d; Le 2 × 500 mg/d
K1a F 49 34 Yesd 133 118 Ce 3 × 1500 mg/d; Mo 1 × 400 mg/d Cl 3 × 600 mg/d;
K2a F 56 39 Yesd 7 1 Ce 3 × 1500 mg/d; Cl 2 × 600 mg/d Ce 3 × 1500 mg/d; Cl 2 × 600 mg/d
K3 F 55 30 Yesd 52 52 Ce 3 × 1500 mg/d; Le 2 × 500 mg/d Ce 3 × 1500 mg/d; Le 2 × 500 mg/d
K4 M 75 37 No 95 81 Ce 3 × 1500 mg/d; Mo 1 × 400 mg/d Ce 3 × 1500 mg/d; Mo 1 × 400 mg/d
K5 F 73 27 No 178 176 Cl 2 × 600 mg/d Ce 3 × 1500 mg/d
K6 F 75 27 Yesd 29 26 Ce 3 × 1500 mg/d; Mo 1 × 400 mg/d Ce 3 × 1500 mg/d; Le 2 × 500 mg/d
K7 F 73 31 Yesd 8 8 Ce 3 × 1500 mg/d; Le 2 × 500 mg/d Ce 3 × 1500 mg/d
K8 F 73 37 Yesc 78 77 Ri 1 × 600 mg/d; Le 1 × 500 mg/d; Fl 4 × 2000 mg/d Cl 3 × 600 mg/d; Le 2 × 500 mg/d
Mean/total 9 M/9 F 67.1 ± 9.4 30.4 ± 5.4 8 76.4 ± 58.9 68.8 ± 59.1

Cumulative data of all patients are either presented as mean ± SD or total number.

H = hip patient; K = knee patient; Antibiotics: Ce = Cefuroxim, Cl = Clindamycin, Fl = Flucloxacillin, Le = Levofloxacin, Mo = Moxifloxacin, Ri = Rifampicin, Va = Vancomycin, all systemic antibiotic treatment within the first 48 h after operation was administered intravenously.

a

Patient excluded from analysis of wound exudate due to missing sample at spacer explantation.

b

Patient excluded from analysis of vancomycin release due to systemic antibiotics therapy with vancomycin at time point of sample collection.

c

Wound revisions and debridements.

d

Partial or total component exchange surgery.