Table 2.
Response and remission rates at the end of treatment in patients with Crohn’s disease or ulcerative colitis.
| Outcome | Crohn’s diseasea (n = 38) | Ulcerative colitisb (n = 47) | All (n = 85) |
|---|---|---|---|
| Response % (95% CIc) | 65.8 (49.8–78.9) | 55.3 (41.2–68.6) | 60.0 |
| Remission % (95% CIc) | 47.4 (32.5–62.7) | 48.9 (35.3–62.8) | 48.2 |
Patients who terminated the study before Week 30 were considered to be non-responders/non-remitters.
a
Clinical response was defined as a decrease of >70 points from the baseline Crohn’s Disease Activity Index (CDAI) score; clinical remission was defined as a CDAI score of 150 or less11.
b
Clinical response was defined as a ≥3 point decrease from the baseline partial Clinical Activity Index (pCAI) score and an absolute sub-score for bleeding not greater than 1 point; clinical remission was defined as a total pCAI score of 2 points or lower12,13.
c
Calculated using the Agresti-Coull method.