Table 3.
Comparison of laboratory data between elderly and young patients with leptospirosis.
| ≥60 years (N = 64) |
<60 years (N = 443) |
p | |
|---|---|---|---|
| Hemoglobin (g/dL) | 10.6 ± 2.5 | 11.1 ± 2.1 | 0.081 |
| Hematocrit (%) | 31.6 ± 7.2 | 33.0 ± 6.6 | 0.141 |
| Leukocytes (103/mm3) | 15.4 ± 6.5 | 13.6 ± 10.3 | 0.003 |
| Platelets (103/mm3) | 103.3 ± 94.6 | 112.6 ± 107.7 | 0.432 |
| Urea (mg/dL) | 176 ± 100 | 133 + 89 | 0.002 |
| Creatinine (mg/dL) | 3.83 ± 2.35 | 3.81 ± 2.86 | 0.498 |
| Sodium (mEq/L) | 134.6 ± 7.2 | 136.5 ± 14.9 | 0.005 |
| Potassium (mEq/L) | 3.8 ± 1.0 | 4.1 ± 0.9 | 0.029 |
| AST (U/L) | 105 (12–422) | 149 (9–1832) | 0.383 |
| ALT (U/L) | 66 (8–734) | 75 (12–1770) | 0.759 |
| Albumin (g/dL) | 3.02 ± 0.55 | 3.18 ± 0.62 | 0.239 |
| Total Bilirubin (mg/dL) | 11.3 (0.22–33.8) | 9.7 (0.13–60.78) | 0.463 |
| Direct Bilirubin (mg/dL) | 10.1 (0.19–30.0) | 9.4 (0.05–46.0) | 0.257 |
| Indirect Bilirubin (mg/dL) | 3.7 (0.03–16.9) | 4.0 (0.02–24.65) | 0.852 |
| LDH (U/L) | 854 ± 576 | 777 ± 547 | 0.655 |
| CPK (U/L) | 930 (31–7,515) | 942 (3–19,690) | 1.000 |
| pH | 7.38 ± 0.09 | 7.36 ± 0.09 | 0.143 |
| HCO3 (mEq/L) | 17.9 ± 4.4 | 19.0 ± 4.8 | 0.168 |
AST – aspartate aminotransferase; ALT – alanine aminotransferase; LDH – lactate dehydrogenase; CPK – creatine phosphokinase; HCO3 – serum bicarbonate. Mann Whitney U and Student t tests were used. P < 0.05 was considered statistically significant. Data were presented as mean ± SD for variables with normal distribution and median (range) for variables with non-normal distribution.