. 2019 Mar 18;28(13):2245–2254. doi: 10.1093/hmg/ddz055

Table 2.

Linear regression of nine respiratory function and skeletal muscle measures against sex, age, height, weight, ePAL and AciI sensitivity

		MIP	MEP	FVC	PEF	Grip	Pinch	Shoulder	Knee	Ankle
Sex	β	0.198	0.238	0.206	0.217	0.121	0.222	0.627	0.496	0.221
Sex	P-value	0.008^*	0.001	0.006^*	0.034^*	0.112	<0.001^*	<0.001^*	<0.001^*	0.008^*
Age	β	−0.426	−0.198	−0.333	−0.337	−0.105	−0.192	−0.119	−0.314	−0.237
Age	P-value	<0.001^*	0.006^*	<0.001^*	<0.001^*	0.057^*	0.001^*	0.072	0.001^*	0.011^*
Height	β	0.071	−0.013	0.465	0.285	0.161	0.045	0.145	0.000	0.056
Height	P-value	0.503	0.903	<0.001^*	0.006^*	0.002^*	0.546	0.107	0.997	0.648
Weight	β	0.041	0.129	−0.246	−0.017	0.006	0.080	0.321	0.245	0.067
Weight	P-value	0.595	0.071^*	<0.001^*	0.831	0.918	0.135	<0.001^*	0.004^*	0.451
log(ePAL)	β	−0.387	−0.590	−0.468	−0.485	−0.718	−0.724	−0.271	−0.283	−0.580
log(ePAL)	P-value	<0.001^*	<0.001^*	<0.001^*	<0.001^*	<0.001^*	<0.001^*	<0.001^*	0.002^*	<0.001^*
AciI sensitivity	β	−0.053	−0.057	0.125	−0.066	0.116	0.217	0.173	0.226	0.264
AciI sensitivity	P-value	0.471	0.414	0.015^*	0.364	0.002^*	0.001^*	0.004^*	0.004^*	0.002^*
Adjusted r²		0.244	0.347	0.586	0.376	0.495	0.522	0.655	0.419	0.317
Significance (P-value)		<0.001	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001
Participants (n)		144	142	166	125	189	188	106	105	106

The table shows the adjusted r² and P-value for each model and the standardized contribution (β) and significance (P-value) of each individual component of the model. The strongest contributor to each model (as determined from the standardized β) is shown in bold font. Only parameters considered significant (marked with an ^*) were included in the adjusted r². Also shown is the number of participants (n) for which each phenotype measure was available.