. 2019 Mar 18;28(13):2245–2254. doi: 10.1093/hmg/ddz055

Table 3.

Linear regression of nine respiratory function and skeletal muscle measures against sex, age, height, weight, modal allele length and AciI sensitivity

		MIP	MEP	FVC	PEF	Grip	Pinch	Shoulder	Knee	Ankle
Sex	β	0.189	0.223	0.200	0.215	0.099	0.174	0.511	0.478	0.191
Sex	P-value	0.010^*	0.002^*	0.007^*	0.037^*	0.175	0.001^*	<0.001^*	<0.001^*	0.017^*
Age	β	−0.423	−0.192	−0.340	−0.336	−0.120	−0.199	−0.111	−0.330	−0.234
Age	P-value	<0.001^*	0.007^*	<0.001^*	<0.001^*	0.025^*	<0.001^*	0.084^*	<0.001^*	0.009^*
Height	β	0.045	−0.056	0.467	0.260	0.136	0.010	0.149	0.014	0.052
Height	P-value	0.671	0.582	<0.001^*	0.011^*	0.007^*	0.896	0.094^*	0.901	0.664
Weight	β	0.039	0.129	−0.237	−0.014	−0.003	0.088	0.299	0.266	0.079
Weight	P-value	0.607	0.066^*	<0.001^*	0.863	0.952	0.084^*	<0.001^*	0.001^*	0.365
log(modal)	β	−0.401	−0.611	−0.489	−0.477	−0.757	−0.782	−0.312	−0.348	−0.634
log(modal)	P-value	<0.001^*	<0.001^*	<0.001^*	<0.001^*	<0.001^*	<0.001^*	<0.001^*	<0.001^*	<0.001^*
AciI sensitivity	β	−0.083	−0.104	0.086	−0.106	0.082	0.125	0.124	0.199	0.145
AciI sensitivity	P-value	0.257	0.127	0.086^*	0.144	0.101	0.010^*	0.031^*	0.008^*	0.069^*
Adjusted r²		0.256	0.377	0.598	0.371	0.531	0.580	0.670	0.446	0.350
Significance (P-value)		<0.001	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001

The table shows the adjusted r² and P-value for each model and the contribution (β) and significance (P-value) of each individual component of the model. The strongest contributor to each model (as determined from the standardized β) is shown in bold font. Only components considered significant (marked with an ^*) were included in the adjusted r².