Table 1.
Selected Demographic Characteristics of Pregnant Women Who Received Tdap During Pregnancy by Vaccination Status Recorded in the Vaccine Safety Datalink Sites From January 1, 2007, Through November 15, 2013
| No. (%) |
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|---|---|---|---|---|
| Time Since Prior Tetanus-Containing Vaccination, y |
||||
| Variable | <2 (n = 4812) |
2–5 (n = 9999) |
>5 (Control) (n = 14 344) |
P Value |
| Maternal age, mean (range), y | 30.5 (15–49) | 30.7 (14–49) | 28.8 (14–48) | <.001 |
| Enrollment prior to pregnancy, mean (range), mo | 49.8 (6.0–99.9) | 62.4 (6.0–100.5) | 63.9 (6.0–99.8) | <.001 |
| Gestational age at Tdap, mean (range), wk | 30 (1–39) | 30 (1–41) | 27 (1–40) | <.001 |
| Adequate prenatal carea | 3629 (75) | 7324 (73) | 10 542 (73) | .01 |
| Other vaccines in pregnancy | 3012 (63) | 6179 (62) | 8996 (63) | .33 |
| Maternal comorbidityb | 1383 (29) | 2956 (30) | 4394 (31) | .03 |
| Pregnancy complicationc | 2514(52) | 5230 (52) | 7565 (53) | .74 |
| Prior tetanus vaccine Tdapd | 4542 (94) | 8511 (85) | 2477 (17) | <.001 |
Abbreviation: Tdap, tetanus, diphtheria, and acellular pertussis.
Adequate or adequate plus prenatal care based on Kotelchuck Adequacy of Prenatal Care Utilization Index.
Presence of hypertension in pregnancy, diabetes, cardiovascular disease, or asthma.
Includes any of the following diagnoses: fetal abnormality affecting maternal management, fetal or placental problems affecting maternal management, polyhydramnios, oligohydramnios, premature rupture of membranes, amnionitis, antepartum hemorrhage, placental abruption, placenta previa, or antepartum complications.
Compared with non-Tdap tetanus vaccines (ie, tetanus diphtheria; tetanus toxoid; diphtheria and tetanus toxoids and acellular pertussis, etc).