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. Author manuscript; available in PMC: 2019 Sep 1.
Published in final edited form as: Adv Mater. 2018 Jul 4;30(37):e1707634. doi: 10.1002/adma.201707634

Figure 2.

Figure 2

(a) Scheme showing the encapsulation of small molecules into ZIF-8 during nMOF growth. (b) Fluorescein release profiles in PBS (black squares) and pH 6.0 buffer solution (red circles). (c) TEM image of fluorescein-encapsulated nanospheres dispersed in PBS for one day. (d) Cell viability when incubated with micron-sized ZIF-8 (dark gray), 70 nm ZIF-8 (light gray), and CPT encapsulated ZIF-8 (white). (e) Cell viability when incubated with free CPT (dark gray), and CPT-encapsulated ZIF-8 (light gray) for 24 h. (f) Fluorescence microscopy images of cells incubated with 70 nm fluorescein-encapsulated ZIF-8. (g) Fe3O4@ZIF-8 nanospheres migrated to sides of a vial upon application of an external magnetic field; inset: TEM image of single Fe3O4@ZIF-8 nanosphere. Reproduced with permission.[53] Copyright 2014, American Chemical Society.