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. 2019 Jun 20;14(6):e0217424. doi: 10.1371/journal.pone.0217424

Table 3. Predictors of AKI in derivation cohorts (n = 455).

OR 95% CI p-value
Lower Upper
Obese vs non-obese 1.28 0.72 2.26 0.399
eGFR < 90 (ml/min/1.73 mq) 2.78 1.78 4.35 <0.001
SOFA cv ≥2 2.23 1.48 3.37 <0.001
Lactate ≥2 (mmol/L) 1.81 1.19 2.74 0.005
(TIMP-2)•(IGFBP7) ≥ 0.3 ((ng/ml)2/1000) 1.65 1.08 2.52 0.019

eGFR = estimated glomerular filtration rate SOFAcv = cardiovascular sequential organ failure assessment; TIMP-2, tissue inhibitor of metalloproteinases 2.; IGFBP7, insulin-like growth factor-binding protein 7