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. 2019 Jun 20;14(6):e0218432. doi: 10.1371/journal.pone.0218432

Fig 2. In vivo HDL regulates specific miRNAs during IR injury.

Fig 2

Mice were sham operated (sham) or submitted to LAD occlusion for 45min and hearts were reperfused for 8h (IR). HDL was injected or not one min before reperfusion. miRNA was isolated from total heart and miRNA expression assessed by microarray analysis after 8h of reperfusion in in vivo mouse hearts using GeneChip miRNA 2.0 Arrays. A) miRNA expression significant change (p<0.05) between sham and IR group (Heatmap representation). B) Expression of miR-34b and miR-337 (boxplot representation). n = 3. *: p<0.05 vs sham, #: p<0.05 vs IR.