Table 7.
Comparison Between our Initial Data Set and This New Cohort of Patients With ALD
| Parameter | Initial Data Set | ALD | PBC | AIH |
|---|---|---|---|---|
| Patients | 136 | 51 | 24 | 20 |
| Cutoff for METAVIR F≥2 fibrosis, kPa | 7.29 | 7.29 | 7.29 | 7.29 |
| Sensitivity (95% CI), % | 91.4 (75.6–97.8) (32/35) | 88.9 (67.2–96.9) (16/18) | 87.5 (52.9–97.8) (7/8) | 85.7 (48.7–97.4) (6/7) |
| Specificity (95% CI), % | 52.5 (42.3–62.4) (53/101) | 39.4 (24.7–56.3) (13/33) | 43.8 (23.1–66.8) (7/16) | 38.5 (17.7–64.5) (5/13) |
| PPV (95% CI), % | 40.0 (29.4–51.6) (32/80) | 44.4 (29.5–60.4) (16/36) | 43.8 (23.1–66.8) (7/16) | 42.9 (21.4–67.4) (6/14) |
| NPV (95% CI), % | 94.6 (84.2–98.6) (53/56) | 86.7 (62.1–96.3) (13/15) | 87.5 (52.9–97.8) (7/8) | 83.3 (43.6–97.0) (5/6) |
| Positive LR (95% CI) | 1.92 (1.53–2.41) | 1.47 (1.07–2.02) | 1.56 (0.94–2.58) | 1.39 (0.82–2.36) |
| Negative LR (95% CI) | 0.16 (0.05–0.49) | 0.28 (0.07–1.11) | 0.29 (0.04–1.94) | 0.37 (0.05–2.59) |