Skip to main content
. Author manuscript; available in PMC: 2019 Oct 5.
Published in final edited form as: ACS Catal. 2018 Sep 5;8(10):9292–9297. doi: 10.1021/acscatal.8b03014

Table 2.

C(sp3)–H Arylation of Weinreb Amides: Substrate Scopea,b,c

graphic file with name nihms-1035408-t0003.jpg
a

Conditions: 1a-1v (0.1 mmol), Pd(OAc)2 (10 mol%), L2 (12 mol%), methyl 4-iodobenzoate (0.2 mmol), AgOAc (0.2 mmol), HFIP (0.5 mL), 80 °C, under air, 24 h.

b

Isolated yield.

c

The numbers in parentheses indicate the ratio of mono:di.