Table 4.

Default mode network (DMN) connectivity in healthy controls versus cLBP patients, pre- and post-physical maneuvers, which temporarily exacerbated clinical pain.

side			size (mm3)	MNI coordinates			peak z-stat
				X (mm)	Y (mm)	Z (mm)
cLBPpre versus healthy controls
S1	L		3,744	−6	−24	54	3.64
thalamus	L		3,184	−18	−38	4	3.49
S1	L		3,032	−62	−20	32	−3.83
cLBPpost versus healthy controls
precuneus	R		7,544	34	−76	34	3.63
cLBPpost versus cLBPpre
• All cLBP patients
mPFC		R	3,672	4	52	−4	4.34
MT+		R	7,888	44	−80	10	4.56
S1/M1		R	5,368	2	−36	66	−3.72
pons		L	3,424	−12	−24	−34	−3.81
• high-PCS cLBP subgroup
anterior/mid insula		R	2,992	40	4	0	3.34
• mid-PCS cLBP subgroup
cuneus			9,248	0	76	14	−4.28
dlPFC		R	2,792	46	44	8	−4.09
• low-PCS cLBP subgroup
mPFC		R	4,880	4	38	−12	4.63
S1/M1		R	4,640	10	−28	72	−4.37

S1=primary sensory cortex, mPFC=medial prefrontal cortex, dlPFC=dorsolateral prefrontal cortex