Table 1.
Correlation between expression of CHD1, cohesin and condensin encoding genes in PCA samples.
| Gene* | PCA samples (total) | P-value | PCA samples with CHD1Δ | P-value |
|---|---|---|---|---|
| CHL1/DDX11 | ||||
| DDX11 | 0.05 | 0.216 | −0.16 | 0.2469 |
| Cohesin core subunits | ||||
| SMC1A | 0.7 | 2.2e-16 | 0.5 | 0.0002088 |
| SMC3 | 0.67 | 2.2e-16 | 0.52 | 8.849e-05 |
| RAD21** | 0.41 | 2.2e-16 | 0.47 | 0.000465 |
| STAG1 | 0.73 | 2.2e-16 | 0.51 | 0.0001186 |
| STAG2 | 0.67 | 2.2e-16 | 0.59 | 6.446e-06 |
| Cohesin regulators | ||||
| WAPL | 0.68 | 2.2e-16 | 0.63 | 8.289e-07 |
| PDS5A | 0.75 | 2.2e-16 | 0.57 | 1.133e-05 |
| PDS5B | 0.57 | 2.2e-16 | 0.61 | 2.469e-06 |
| NIPBL | 0.61 | 2.81e-53 | 0.55 | 0.0007 |
| ESCO1 | 0.42 | 2.61e-22 | 0.48 | 0.004 |
| Condensin | ||||
| SMC2 | 0.44 | 2.2e-16 | 0.44 | 0.001371 |
| SMC4 | 0.42 | 2.2e-16 | 0.34 | 0.01378 |
| Condensin I | ||||
| NCAPH | 0.06 | 0.1251 | −0.13 | 0.3626 |
| NCAPD2 | 0.42 | 2.2e-16 | 0.04 | 0.0033 |
| NCAPG | 0.12 | 0.006 | 0.02 | 0.864 |
| Condensin II | ||||
| NCAPH2 | −0.36 | 2.2e-16 | −0.31 | 0.02793 |
| NCAPD3 | −0.02 | 0.62 | 0 | 0.945 |
| NCAPG2 | 0.36 | 2.2e-16 | 0.21 | 0.1401 |
*Genes with significant Pearson’s correlations are in Italic.
**Pearson’s correlation is close to statistical significance of 0.5.