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. 2019 Jun 20;9:8871. doi: 10.1038/s41598-019-45404-8

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Stimulus-evoked fMRI activation map (A) Localization of activated digit regions in areas 3b and 1 of one representative squirrel monkey (SM-ZT) in response to vibrotactile stimulation of the D3 tip. Normalized percentage signal change maps were thresholded at 0.7. Dotted black lines indicate the approximate borders between areas 3b and 1, and between digit and face. Blue boxes show the selected seed voxels used in subsequent resting state functional connectivity analysis. (B) Optical image showing blood vessels and the two 7 × 7 multi-channel electrode arrays inserted in the corresponding digit regions of areas 3b and 1 under surgical microscope guidance in the same monkey (SM-ZT). (Scale bar, 1 mm.) a, anterior; m, medial.