Figure 1.

Representative B-mode and elastography images acquired during and after completion of chemotherapy. (A) Representative ultrasound B-mode and elastography images from a pCR patient's tumor taken at baseline; weeks 1, 4, and 8; and after completion of chemotherapy (preop). The responding patient demonstrated progressive changes in both tumor morphology and tumor strain. (B) Representative ultrasound B-mode and elastography images from an npCR patient's tumor taken at baseline; weeks 1, 4, and 8; and after completion of chemotherapy (preop). SR changed significantly for the nonresponder over the course of treatment, however, to a lesser degree than the change seen with the pCR patient. Static (fixed-sized) ROIs were used in selecting the tumor region to estimate strain values for each patient. Scale bar = 1 cm, color bar = hard (blue) to soft (red) (0 to 255).