Table 2.
Summary of Statistical Measures and Results.
| Decrease in SR from Baseline (% ± SD) |
||
|---|---|---|
| pCR: RS5 (n = 21) | Non-pCR: RS1-4 (n = 71) | |
| Week 1 | 4 ± 13 | −1 ± 9 |
| Week 2 | 12 ± 13* | 3 ± 11* |
| Week 4 | 19 ± 13** | 6 ± 11** |
| Week 8 | 25 ± 16** | 9 ± 11** |
| Week 12 | 30 ± 17** | 14 ± 13** |
| Preoperative | 29 ± 15** | 12 ± 13** |
| Decrease in SR from Baseline (% ± SD) | ||
| RS4-5 (n = 37) | RS1-3 (n = 39) | |
| Week 1 | 3 ± 11 | −1 ± 9 |
| Week 2 | 7 ± 13 | 2 ± 9 |
| Week 4 | 11 ± 15 | 6 ± 10 |
| Week 8 | 17 ± 16* | 9 ± 11* |
| Week 12 | 21 ± 18* | 14 ± 13* |
| Preoperative | 20 ± 16* | 13 ± 13* |
| Decrease in SR from Baseline (% ± SD) | ||
| RS3-5 (n = 66) | RS1-2 (n = 10) | |
| Week 1 | 0 ± 10 | 0 ± 7 |
| Week 2 | 5 ± 12 | 1 ± 8 |
| Week 4 | 9 ± 13 | 4 ± 10 |
| Week 8 | 14 ± 15 | 7 ± 10 |
| Week 12 | 18 ± 15 | 15 ± 23 |
| Preoperative | 17 ± 15 | 12 ± 14 |
SRs for each response group, as categorized by the indicated Miller-Payne criteria, were analyzed for statistical differences over time using a repeated-measures ANOVA. Responders and nonresponders were compared to each other at each time interval to test for statistically significant differences following a test for normality (Shapiro-Wilk Test). Statistically significant, *P < .05; very statistically significant, **P < .001.