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. 2019 Jun 20;9:8834. doi: 10.1038/s41598-019-45456-w

Figure 5.

Figure 5

The gap junction blocker carbenoxolone does not affect the frequency of responsive tracheal epithelial cells to denatonium and saccharin. (a) Representative calcium transients recorded from three individual tracheal epithelial cells in response to 5 mM denatonium (blue traces) or 30 µM ATP (black traces) before and after application of 100 µM carbenoxolone (Cbx). (b) Calcium transients in response to 20 mM saccharin (green traces) or 30 µM ATP (black traces) before and after application of 100 µM carbenoxolone. (c,d) Heat maps of normalized change in fluorescence intensity following stimulation with the indicated compounds before and after application of 100 µM carbenoxolone.