Table 2.
Effects of KP extract on hematological parameters in rats treated orally for 90 days.
Parameter | Group (females) |
Group (males) |
||||||
---|---|---|---|---|---|---|---|---|
Control | Low-dose | Medium-dose | High-dose | Control | Low-dose | Medium-dose | High-dose | |
WBC (109/L) | 54.5 ± 10.9 | 63.2 ± 12.4 | 42.1 ± 9.0 | 47.5 ± 8.6 | 96.5 ± 12.8 | 91.7 ± 17.4 | 97.8 ± 32.3 | 106.0 ± 24.1 |
RBC (1012/L) | 724.4 ± 21.9 | 752.6 ± 30.1 | 708.0 ± 10.2 | 724.0 ± 21.6 | 788.6 ± 41.2 | 788.8 ± 32.4 | 791.8 ± 35.7 | 770.4 ± 11.5 |
HG (g/L) | 14.3 ± 0.2 | 14.5 ± 0.6 | 14.0 ± 0.4 | 14.1 ± 0.2 | 14.7 ± 0.6 | 15.0 ± 0.5 | 14.7 ± 0.8 | 14.5 ± 0.2 |
HC (%) | 39.3 ± 0.8 | 39.4 ± 1.1 | 37.9 ± 1.1 | 38.6 ± 0.9 | 40.4 ± 1.2 | 41.3 ± 1.2 | 40.3 ± 2.2 | 40.0 ± 0.5 |
PLT (1012/L) | 82.8 ± 9.1 | 100.4 ± 12.5* | 88.6 ± 10.3 | 83.3 ± 5.7 | 96.2 ± 3.4 | 93.3 ± 11.7 | 104.4 ± 13.7 | 96.7 ± 9.9 |
MCV (fL) | 54.3 ± 1.3 | 52.3 ± 1.0 | 53.6 ± 1.6 | 53.4 ± 1.2 | 51.3 ± 1.5 | 52.4 ± 2.2 | 50.9 ± 2.3 | 52.0 ± 1.3 |
MCH (pg) | 19.8 ± 0.6 | 19.2 ± 0.4 | 19.8 ± 0.6 | 19.5 ± 0.5 | 18.7 ± 0.5 | 19.0 ± 0.5 | 18.5 ± 0.8 | 18.8 ± 0.5 |
MCHC (g/dL) | 36.5 ± 0.4 | 36.8 ± 0.6 | 37.0 ± 0.2 | 36.5 ± 0.5 | 36.5 ± 0.4 | 36.3 ± 0.6 | 36.4 ± 0.4 | 36.1 ± 0.4 |
Lymphocytes (%) | 78.3 ± 8.5 | 82.4 ± 8.2 | 80.8 ± 6.0 | 85.3 ± 1.3 | 79.3 ± 4.0 | 81.9 ± 4.7 | 82.4 ± 2.0 | 83.5 ± 3.5 |
Neutrophils (%) | 16.8 ± 8.1 | 12.9 ± 8.3 | 14.1 ± 4.9 | 10.0 ± 0.4 | 15.3 ± 3.4 | 12.8 ± 4.1 | 12.7 ± 1.3 | 12.1 ± 2.7 |
Other (%) | 4.9 ± 1.1 | 4.7 ± 2.1 | 5.1 ± 1.3 | 4.7 ± 1.5 | 5.4 ± 0.7 | 5.3 ± 1.9 | 4.9 ± 1.3 | 4.4 ± 1.6 |
Results are shown as means ± standard deviation (n = 5).
Low dose: 25 mg/kg bw/day; medium dose: 125 mg/kg bw/day; high dose: 249 mg/kg bw/day.
Abbreviations: WBC, white blood cell count; RBC, red blood cell count; HG, hemoglobin; HC, hematocrit; PLT, platelet count; MCV, mean corpuscular volume; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration.
Statistically significant difference relative to the control (p < 0.05).