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. 2019 Jun 7;6:544–549. doi: 10.1016/j.toxrep.2019.06.003

Table 2.

Effects of KP extract on hematological parameters in rats treated orally for 90 days.

Parameter Group (females)
Group (males)
Control Low-dose Medium-dose High-dose Control Low-dose Medium-dose High-dose
WBC (109/L) 54.5 ± 10.9 63.2 ± 12.4 42.1 ± 9.0 47.5 ± 8.6 96.5 ± 12.8 91.7 ± 17.4 97.8 ± 32.3 106.0 ± 24.1
RBC (1012/L) 724.4 ± 21.9 752.6 ± 30.1 708.0 ± 10.2 724.0 ± 21.6 788.6 ± 41.2 788.8 ± 32.4 791.8 ± 35.7 770.4 ± 11.5
HG (g/L) 14.3 ± 0.2 14.5 ± 0.6 14.0 ± 0.4 14.1 ± 0.2 14.7 ± 0.6 15.0 ± 0.5 14.7 ± 0.8 14.5 ± 0.2
HC (%) 39.3 ± 0.8 39.4 ± 1.1 37.9 ± 1.1 38.6 ± 0.9 40.4 ± 1.2 41.3 ± 1.2 40.3 ± 2.2 40.0 ± 0.5
PLT (1012/L) 82.8 ± 9.1 100.4 ± 12.5* 88.6 ± 10.3 83.3 ± 5.7 96.2 ± 3.4 93.3 ± 11.7 104.4 ± 13.7 96.7 ± 9.9
MCV (fL) 54.3 ± 1.3 52.3 ± 1.0 53.6 ± 1.6 53.4 ± 1.2 51.3 ± 1.5 52.4 ± 2.2 50.9 ± 2.3 52.0 ± 1.3
MCH (pg) 19.8 ± 0.6 19.2 ± 0.4 19.8 ± 0.6 19.5 ± 0.5 18.7 ± 0.5 19.0 ± 0.5 18.5 ± 0.8 18.8 ± 0.5
MCHC (g/dL) 36.5 ± 0.4 36.8 ± 0.6 37.0 ± 0.2 36.5 ± 0.5 36.5 ± 0.4 36.3 ± 0.6 36.4 ± 0.4 36.1 ± 0.4
Lymphocytes (%) 78.3 ± 8.5 82.4 ± 8.2 80.8 ± 6.0 85.3 ± 1.3 79.3 ± 4.0 81.9 ± 4.7 82.4 ± 2.0 83.5 ± 3.5
Neutrophils (%) 16.8 ± 8.1 12.9 ± 8.3 14.1 ± 4.9 10.0 ± 0.4 15.3 ± 3.4 12.8 ± 4.1 12.7 ± 1.3 12.1 ± 2.7
Other (%) 4.9 ± 1.1 4.7 ± 2.1 5.1 ± 1.3 4.7 ± 1.5 5.4 ± 0.7 5.3 ± 1.9 4.9 ± 1.3 4.4 ± 1.6

Results are shown as means ± standard deviation (n = 5).

Low dose: 25 mg/kg bw/day; medium dose: 125 mg/kg bw/day; high dose: 249 mg/kg bw/day.

Abbreviations: WBC, white blood cell count; RBC, red blood cell count; HG, hemoglobin; HC, hematocrit; PLT, platelet count; MCV, mean corpuscular volume; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration.

*

Statistically significant difference relative to the control (p <  0.05).