Table 3.
Parameter | Group (females) |
Group (males) |
||||||
---|---|---|---|---|---|---|---|---|
Control | Low-dose | Medium-dose | High-dose | Control | Low-dose | Medium-dose | High-dose | |
AST (U/L) | 64.2 ± 2.9 | 69.4 ± 9.8 | 59.4 ± 5.4 | 67.4 ± 27.3 | 94.2 ± 24.8 | 71.6 ± 15.8 | 87.8 ± 31.8 | 83.2 ± 17.6 |
ALT (U/L) | 26.6 ± 4.8 | 31.6 ± 5.5 | 26.2 ± 3.4 | 28.4 ± 12.1 | 40.4 ± 18.3 | 29.4 ± 5.9 | 34.4 ± 11.8 | 35.4 ± 7.2 |
ALP (U/L) | 110.4 ± 23.2 | 121.6 ± 34.4 | 147.4 ± 45.1 | 139.0 ± 88.1 | 248.2 ± 56.3 | 246.2 ± 65.9 | 236.4 ± 13.3 | 291.8 ± 63.4 |
Total protein (g/L) | 61.0 ± 4.0 | 61.8 ± 4.0 | 64.2 ± 4.8 | 62.6 ± 2.9 | 56.2 ± 1.3 | 57.0 ± 2.4 | 53.8 ± 2.8 | 55.4 ± 3.5 |
Albumin (g/L) | 30.2 ± 2.8 | 31.0 ± 2.3 | 32.4 ± 3.1 | 31.0 ± 2.1 | 24.0 ± 1.0 | 23.8 ± 0.8 | 22.8 ± 1.3 | 24.2 ± 1.6 |
BUN (mmol/L) | 6.44 ± 0.48 | 6.45 ± 1.15 | 5.38 ± 0.84 | 6.13 ± 1.25 | 5.79 ± 0.37 | 5.88 ± 0.29 | 6.26 ± 0.54 | 5.91 ± 0.58 |
CRE (mmol/L) | 33.59 ± 7.40 | 33.59 ± 3.95 | 31.82 ± 4.84 | 26.52 ± 0.00 | 30.06 ± 4.84 | 26.52 ± 6.25 | 30.06 ± 4.84 | 24.75 ± 3.95 |
T-BIL (μmol/L) | 1.0 ± 0.9 | 1.0 ± 0.9 | 1.0 ± 1.5 | 1.4 ± 0.8 | 0.7 ± 0.9 | 0.7 ± 0.9 | 0.0 ± 0.0 | 0.0 ± 0.0 |
Glucose (mmol/L) | 81.38 ± 10.06 | 82.82 ± 9.77 | 81.04 ± 6.79 | 79.93 ± 5.30 | 84.71 ± 10.06 | 85.04 ± 13.39 | 80.71 ± 8.81 | 85.37 ± 12.35 |
T-Cho (mmol/L) | 1.83 ± 0.33 | 1.69 ± 0.18 | 2.16 ± 0.73 | 2.08 ± 0.13 | 1.72 ± 0.27 | 1.83 ± 0.43 | 1.74 ± 0.29 | 2.03 ± 0.44 |
TG (mmol/L) | 0.48 ± 0.10 | 0.61 ± 0.30 | 0.99 ± 0.55 | 0.74 ± 0.24 | 0.72 ± 0.34 | 0.84 ± 0.34 | 0.84 ± 0.61 | 1.03 ± 0.37 |
Results are shown as means ± standard deviation (n = 5).
Low dose: 25 mg/kg bw/day; medium dose: 125 mg/kg bw/day; high dose: 249 mg/kg bw/day.
Abbreviations: AST, aspartate aminotransferase; ALT, alanine aminotransferase; ALP, alkaline phosphatase; BUN, blood urea nitrogen; CRE, creatinine; T-BIL, total bilirubin; T-Cho, total cholesterol; TG, triglycerides.