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. 2019 Jun 7;6:544–549. doi: 10.1016/j.toxrep.2019.06.003

Table 3.

Effects of KP extract on biochemical parameters in rats treated orally for 90 days.

Parameter Group (females)
Group (males)
Control Low-dose Medium-dose High-dose Control Low-dose Medium-dose High-dose
AST (U/L) 64.2 ± 2.9 69.4 ± 9.8 59.4 ± 5.4 67.4 ± 27.3 94.2 ± 24.8 71.6 ± 15.8 87.8 ± 31.8 83.2 ± 17.6
ALT (U/L) 26.6 ± 4.8 31.6 ± 5.5 26.2 ± 3.4 28.4 ± 12.1 40.4 ± 18.3 29.4 ± 5.9 34.4 ± 11.8 35.4 ± 7.2
ALP (U/L) 110.4 ± 23.2 121.6 ± 34.4 147.4 ± 45.1 139.0 ± 88.1 248.2 ± 56.3 246.2 ± 65.9 236.4 ± 13.3 291.8 ± 63.4
Total protein (g/L) 61.0 ± 4.0 61.8 ± 4.0 64.2 ± 4.8 62.6 ± 2.9 56.2 ± 1.3 57.0 ± 2.4 53.8 ± 2.8 55.4 ± 3.5
Albumin (g/L) 30.2 ± 2.8 31.0 ± 2.3 32.4 ± 3.1 31.0 ± 2.1 24.0 ± 1.0 23.8 ± 0.8 22.8 ± 1.3 24.2 ± 1.6
BUN (mmol/L) 6.44 ± 0.48 6.45 ± 1.15 5.38 ± 0.84 6.13 ± 1.25 5.79 ± 0.37 5.88 ± 0.29 6.26 ± 0.54 5.91 ± 0.58
CRE (mmol/L) 33.59 ± 7.40 33.59 ± 3.95 31.82 ± 4.84 26.52 ± 0.00 30.06 ± 4.84 26.52 ± 6.25 30.06 ± 4.84 24.75 ± 3.95
T-BIL (μmol/L) 1.0 ± 0.9 1.0 ± 0.9 1.0 ± 1.5 1.4 ± 0.8 0.7 ± 0.9 0.7 ± 0.9 0.0 ± 0.0 0.0 ± 0.0
Glucose (mmol/L) 81.38 ± 10.06 82.82 ± 9.77 81.04 ± 6.79 79.93 ± 5.30 84.71 ± 10.06 85.04 ± 13.39 80.71 ± 8.81 85.37 ± 12.35
T-Cho (mmol/L) 1.83 ± 0.33 1.69 ± 0.18 2.16 ± 0.73 2.08 ± 0.13 1.72 ± 0.27 1.83 ± 0.43 1.74 ± 0.29 2.03 ± 0.44
TG (mmol/L) 0.48 ± 0.10 0.61 ± 0.30 0.99 ± 0.55 0.74 ± 0.24 0.72 ± 0.34 0.84 ± 0.34 0.84 ± 0.61 1.03 ± 0.37

Results are shown as means ± standard deviation (n = 5).

Low dose: 25 mg/kg bw/day; medium dose: 125 mg/kg bw/day; high dose: 249 mg/kg bw/day.

Abbreviations: AST, aspartate aminotransferase; ALT, alanine aminotransferase; ALP, alkaline phosphatase; BUN, blood urea nitrogen; CRE, creatinine; T-BIL, total bilirubin; T-Cho, total cholesterol; TG, triglycerides.