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. 2019 Jun 7;6:544–549. doi: 10.1016/j.toxrep.2019.06.003

Table 4.

Effects of KP extract on relative organ weights in rats treated orally for 90 days.

Parameter
Group (females)
Group (males)
Control Low-dose Medium-dose High-dose Control Low-dose Medium-dose High-dose
Liver (g/100 g) 2.55 ± 0.13 2.57 ± 0.27 2.66 ± 0.09 2.68 ± 0.13 2.88 ± 0.21 3.03 ± 0.33 2.69 ± 0.10 3.03 ± 0.25
Kidneys (g/100 g) 0.60 ± 0.02 0.57 ± 0.05 0.62 ± 0.04 0.61 ± 0.04 0.58 ± 0.07 0.56 ± 0.07 0.59 ± 0.05 0.61 ± 0.07
Spleen (g/100 g) 0.20 ± 0.03 0.17 ± 0.01 0.19 ± 0.02 0.17 ± 0.03 0.16 ± 0.02 0.18 ± 0.02 0.18 ± 0.04 0.17 ± 0.03
Thymus (g/100 g) 0.13 ± 0.01 0.12 ± 0.03 0.12 ± 0.01 0.14 ± 0.03 0.08 ± 0.01 0.10 ± 0.02* 0.09 ± 0.00 0.09 ± 0.02
Heart (g/100 g) 0.33 ± 0.05 0.35 ± 0.03 0.32 ± 0.03 0.33 ± 0.02 0.27 ± 0.03 0.32 ± 0.04* 0.27 ± 0.01 0.28 ± 0.02
Brain (g/100 g) 0.63 ± 0.05 0.67 ± 0.06 0.60 ± 0.06 0.60 ± 0.08 0.38 ± 0.02 0.38 ± 0.03 0.36 ± 0.03 0.39 ± 0.04
Lungs (g/100 g) 0.37 ± 0.03 0.36 ± 0.03 0.36 ± 0.02 0.34 ± 0.03 0.27 ± 0.01 0.26 ± 0.03 0.26 ± 0.02 0.27 ± 0.02
Pituitary (mg/100 g) 5.4 ± 1.5 6.0 ± 1.2 5.8 ± 1.3 5.0 ± 1.0 2.4 ± 0.5 2.4 ± 0.9 1.8 ± 0.4 2.4 ± 0.5
Thyroid (mg/100 g) 5.8 ± 1.0 5.9 ± 0.8 5.9 ± 1.3 5.4 ± 0.9 3.7 ± 0.6 4.2 ± 0.4 4.3 ± 0.6 4.6 ± 0.5
Adrenal gland (mg/100 g) 25.5 ± 6.1 23.3 ± 5.7 23.3 ± 3.1 18.3 ± 2.4* 11.1 ± 2.1 10.9 ± 3.2 11.5 ± 2.9 11.0 ± 2.7
Testes (g/100 g) 0.61 ± 0.08 0.61 ± 0.03 0.54 ± 0.03 0.60 ± 0.06
Prostate (g/100 g) 0.25 ± 0.06 0.21 ± 0.12 0.25 ± 0.05 0.27 ± 0.10
Uterus (g/100 g) 0.24 ± 0.04 0.24 ± 0.05 0.27 ± 0.10 0.17 ± 0.01*
Ovaries (mg/100 g) 29.7 ± 7.1 24.3 ± 5.3 26.2 ± 6.0 25.1 ± 5.5

Results are shown as means ± standard deviation (n = 5).

Low dose: 25 mg/kg bw/day; medium dose: 125 mg/kg bw/day; high dose: 249 mg/kg bw/day.

*

Statistically significant difference relative to the control (p <  0.05).