Fig. 1.

Experimental design. a) Immediately following a baseline fMRI scan, amputee participants started approximately four weeks of mirror therapy. The second and third scan sessions were conducted at approximately two-week intervals. Age- and gender-matched control participants underwent the same series of scans at the same time intervals. b) During each scan session, participants viewed images of hands and feet from the left or right side of the body in a block design. Within each block, limb and side of body were fixed and images from each side were presented in the congruent screen location (e.g., left foot on left side of screen). Only one image was presented at a time, and participants were asked to fixate at the center of the screen throughout each scan.