Table 1.
Demographic and clinical score in patients with multiple system atrophy and controls.
| Demographic variable | MSA (n = 61) | MSA-C (n = 28) | MSA-P (n = 33) | Control (n = 63) | p value |
|---|---|---|---|---|---|
| Age (mean ± SD) | 62.97 ± 8.53 | 63.83 ± 9.04 | 62.21 + 7.98 | 63.78 + 4.71 | 0.512 |
| Gender (M/F) | 26:35 | 13:15 | 14:19 | 25:38 | 0.742 |
| Education(years) | 12.03 ± 3.72 | 10.76 ± 3.54 | 11.09 ± 4.82 | 11.70 ± 2.53 | 0.559 |
| Duration of disease (years) | 3.37 ± 1.86 | 3.47 ± 1.60 | 3.27 ± 2.08 | – | 0.75# |
| MoCA | 22.39 ± 3.91 | 21.76 ± 4.06 | 22.39 ± 4.75 | 26.98 ± 1.09 | 0.00* |
| UMSARS | 30.43 ± 17.99 | 32.59 ± 20.79 | 30.12 ± 17.53 | – | 0.61# |
| Lateral onset(L/R/Nlo) | 16/33/12 | 5/16/7 | 11/17/5 | – | 0.149# |
SD, standard deviation; MSA: multiple system atrophy; MSA-P: MSA-parkinsonian variant; MSA-C: MSA-cerebellar variant; HC: healthy controls; UMSARS: Unified Multiple System Atrophy Rating Scale; MoCA: Montreal Cognitive Assessment; 0.00*: values <0.000; 0.75#: comparison between MSA-P and MSA-C; Nlo: Non lateralized onset.