Table 3.
Brain regions with significant cerebellar GMV differences between MSA subtypes and HC group.
| Index brain region | Cluster size |
Peak MNI coordinates |
T values | ||
|---|---|---|---|---|---|
| (voxels) | X | Y | Z | ||
| MSAc < HC | |||||
| 1 Cerebellum crus IX_R (AAL) | 140 | 14 | −-48 | −-47 | −-6.153 |
| 2 Cerebellum crus II_L (AAL) | 189 | −-40 | −-62 | −-43 | −-6.238 |
| 3 Cerebellum _IV-V_L (AAL) | 136 | −-4 | −-42 | −-15 | −-5.666 |
| 4 Cerebellum _IX_L (AAL) | 89 | −-10 | −-46 | −-47 | −-5.025 |
| 5 Cerebellum _VIII_L (AAL) | 71 | −-8 | −-74 | −-27 | −-5.615 |
| 6 Cerebellum _VIII_R (AAL) | 57 | 8 | −-72 | −-41 | −-5.405 |
| 7 Cerebellum crus II_R (AAL) | 105 | 34 | −-76 | −-39 | −-5.662 |
| 8 Cerebellum crus I_R (AAL) | 72 | 42 | −-64 | −-29 | −-4.774 |
| 9 Cerebellum crus I_L (AAL) | 53 | −-30 | −-52 | −-31 | −-4.536 |
| 10 Cerebellum_ IV_V _R (AAL) | 79 | 4 | −-64 | −-21 | −-6.057 |
| MSAp < HC | |||||
| 1. Cerebellum crus IX_L (AAL) | 41 | −-10 | −-44 | −-53 | −-5.197 |
| 2. Cerebellum crus IX_R (AAL) | 64 | 14 | −-50 | −-45 | −-4.889 |
| 3. Cerebellum _VI_L (AAL) | 23 | −-10 | −-68 | −-21 | −-4.631 |
| 4. Cerebellum _IV-V_R (AAL) | 41 | 14 | −-48 | −-23 | −-5.201 |
| 5. Cerebellum_ IV-V _L (AAL) | 59 | −-6 | −-50 | −-17 | −-4.938 |
| MSAc < MSAp | |||||
| 1. Cerebellum crus II_R (AAL) | 31 | 44 | −-70 | −-41 | −-4.480 |
Clusters of GM identified by SPM analysis (FDR-corrected, p < .05; threshold k > 20 voxels), MSA-P: MSA-parkinsonian variant; MSA-C: MSA-cerebellar variant; HC: healthy controls.