Table 1.
Characteristics of patients according to vital status at 3 months.
| All patients (n = 173) | Alive (n = 141) | Dead (n = 32) | P | |
|---|---|---|---|---|
| Age (years) | ||||
| Median (IQR) | 76.9 (66.3–85.1) | 75.9 (65.7–82.9) | 85.4 (73.1–88.5) | |
| First tertile (n = 58) | 52 (36.9%) | 6 (18.8%) | 0.050 | |
| Second tertile (n = 58) | 51 (36.2%) | 7 (21.9%) | 0.122 | |
| Third tertile (n = 57) | 38 (26.9%) | 19 (59.4%) | <0.001 | |
| Women | 85 (49%) | 73 (52%) | 12 (38%) | 0.145 |
| NIHSS at admission | 11.6 ± 6.5 | 10.3 ± 6.0 | 17.1 ± 5.8 | <0.001 |
| NIHSS at D1 (n = 171) | 7.5 ± 6.8 | 5.6 ± 5.2 | 16.8 ± 7.1 | <0.001 |
| Etiology (TOAST classification) | 0.039 | |||
| Large artery | 26 (15%) | 17 (12%) | 9 (28.1%) | |
| Cardioembolic | 66 (38.2%) | 50 (35.5%) | 16 (50%) | |
| Small vessel disease | 3 (1.7%) | 3 (2.1 %) | 0 | |
| Other causes | 6 (3.5%) | 6 (4.3%) | 0 | |
| Unknown | 71 (41%) | 64 (45.4 %) | 7 (21.9%) | |
| Multiple causes | 1 (0.9%) | 1 (0.7%) | 0 | |
| Cardiovascular risk factors | ||||
| Hypertension | 108 (62.4%) | 84 (59.6%) | 24 (75%) | 0.020 |
| Diabetes mellitus | 27 (15.6%) | 20 (14.2%) | 7 (21.9%) | 0.279 |
| Current smoking | 21 (12.1%) | 20 (14.2%) | 1 (3.1%) | 0.084 |
| Hypercholesterolemia | 58 (33.5%) | 48 (34%) | 10 (31.3%) | 0.763 |
| Previous vascular diseases | ||||
| Previous stroke | 20 (11.6%) | 13 (9.2%) | 7 (21.88%) | 0.037 |
| Previous TIA | 6 (3.5%) | 6 (4.3%) | 0 | 0.250 |
| Myocardial infarction | 13 (7.5%) | 9 (6.4%) | 4 (12.5%) | 0.236 |
| Peripheral artery disease | 7 (4.1%) | 3 (2.1%) | 4 (12.5%) | 0.007 |
| Heart failure | 17 (9.8%) | 10 (7.1%) | 7 (21.9%) | 0.011 |
| Atrial fibrillation | 29 (16.8%) | 21 (14.9%) | 8 (32%) | 0.167 |
| Stroke localization | 0.29 | |||
| MCA/AChoA territory | 150 (87.7%) | 121 (87.0%) | 29 (90.6%) | |
| ACA territory | 4 (2.3%) | 2 (1.4%) | 2 (6.2%) | |
| PCA territory | 9 (5.3%) | 0 (6.5%) | 0 | |
| Cerebellum | 1 (0.6%) | 1 (0.7%) | 0 | |
| Brainstem | 7 (4.1%) | 6 (4.3%) | 1 (3.1%) | |
| Acute revascularization therapy | 0.151 | |||
| IV Thrombolysis only | 99 (57.2%) | 85 (60.3%) | 14 (43.8%) | |
| Thrombectomy only | 41 (23.4%) | 31 (22%) | 10 (31.3%) | |
| Combined therapy | 33 (19.1%) | 25 (17.7%) | 8 (25%) | |
| Biological data | ||||
| GDF-15 D0 (pg/mL) | ||||
| mean, SD | 2,101 ± 1,644 | 1,756 ± 1,203 | 3,622 ± 2,353 | <0.001 |
| Median (IQR) | 1,629 (1,030–2,457) | 1,460 (965–2,079) | 2,777 (1,769–5,446) | |
| CRP (mg/L) | ||||
| Median (IQR) | 13.5 ± 23.9 | 10.1 ± 17.9 | 28.2 ± 38 | 0.001 |
| Creatinine (μmol/L) | ||||
| Median (IQR) | 72 (61–89 | 74 (62–86) | 70 (58–93) | 0.812 |
MCA, middle cerebral artery; AChoA, anterior choroidal artery; ACA, anterior cerebral artery; PCA, posterior cerebral artery.