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. 2019 Jun 14;10:736. doi: 10.3389/fphys.2019.00736

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Copyright © 2019 Møller, Vendelbo, Schjerling, Couppé, Møller, Kjær, Hansen and Jessen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Protein expression of muscle-specific E3-ligases did not change during immobilization. MuRF1 and ATROGIN-1 protein expression did not change during immobilization and rehabilitation (A,B). mRNA expression of MuRF1 increased during immobilization and decreased during the first 2 weeks of rehabilitation (C). Values are geometric means ± back-transformed SE. ^∗Post hoc test showed significant change during immobilization. Representative western blots (D). Based on the applied molecular standards, approximated molecular weights are indicated on the right. Filled symbols represent subjects from T0 and open symbols represent subjects from T2.