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. 2019 Jun 20;5(10). doi: 10.1001/jamaoncol.2019.1094

Table 2. Characteristics of Anesthetic Agents.

Anesthetic Agent Participants Receiving Agent, No. (%) Cumulative Dose per Participant
Mean (SD)a Median (range)
Propofol, mg/kg 212 (100) 148.39 (70.27) 132.35 (40.48-372.98)
Fentanyl, μg/kg 212 (100) 17.46 (7.67) 16.41 (4.81-54.39)
Fluranes (exposures)b 203 (95.8) 2.37 (1.48) 2.00 (0-10.00)
Glycopyrrolate, μg/kg 147 (69.3) 19.58 (23.07) 5.84 (0-166.15)
Pentobarbital sodium, mg/kg 132 (62.3) 20.05 (12.77) 5.89 (0-65.30)
Meperidine hydrochloride, mg/kg 125 (59.0) 4.15 (2.96) 1.08 (0-11.69)
Midazolam hydrochloride, mg/kg 122 (57.6) 0.18 (0.19) 0.04 (0-0.89)
Morphine sulfate, mg/kg 66 (31.1) 0.22 (0.29) 0 (0-1.61)
Rocuronium bromide, mg/kg 47 (22.2) 1.07 (1.08) 0 (0-5.00)
Diazepam, mg/kg 33 (15.6) 0.50 (0.50) 0 (0-2.47)
Neostigmine methylsulfate, mg/kg 29 (13.7) 0.06 (0.03) 0 (0-0.14)
Ketamine hydrochloride, mg/kg 11 (5.2) 2.92 (2.82) 0 (0-8.54)
Vecuronium bromide, mg/kg 8 (3.8) 0.14 (0.09) 0 (0-0.31)
Atropine, mg/kg 8 (3.8) 0.01 (0.00) 0 (0-0.02)
Cisatracurium besylate, mg/kg 7 (3.3) 0.19 (0.09) 0 (0-0.33)
Ephedrine hydrochloride, mg/kg 5 (2.4) 0.39 (0.12) 0 (0-0.49)
Succinylcholine chloride, mg/kg 3 (1.4) 1.22 (0.13) 0 (0-1.37)
a

Mean (SD) cumulative dose is based only on the individuals who received the agent.

b

Number of exposures was identified for fluranes because cumulative dose cannot be accurately captured for inhaled anesthetic agents.