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. 2019 May 25;9(12):3476–3484. doi: 10.7150/thno.31970

Table 2.

Liver tissue reference and lesion metrics using OSEM (3 iterations/16 subsets, and a 5-mm gaussian postprocessing filter) and BSREM image reconstruction, both including TOF and PSF recovery, with an acquisition time of 2 min/bed position. Mean (range).

Reconstruction Background SUVmean Noise BV % SNR SBR
OSEM 5.2 (1.7-8.9) 15.2 (10.6-22.1) 120.9 (21.7-634.2) 4.5 (0.7-46.2)
BSREM β 100 5.2 (1.7-9.1) 36.4 (21.6-62.2) 105.1 (20.4-287.7) 8.2 (2.0-60.9)
BSREM β 200 5.2 (1.7-9.1) 22.3 (14.5-37.2) 136.0 (27.6-448.6) 6.8 (1.4-56.4)
BSREM β 300 5.2 (1.7-9.1) 17.1 (11.7-27.1) 152.2 (31.6-569.8) 6.1 (1.2-54.0)
BSREM β 400 5.2 (1.7-9.1) 14.4 (9.5-21.9) 163.7 (33.1-660.6) 5.7 (1.0-51.9)
BSREM β 500 5.2 (1.7-9.1) 12.8 (8.4-18.6) 171.1 (34.7-719.1) 5.4 (0.9-50.3)
BSREM β 600 5.2 (1.7-9.1) 11.7 (7.5-17.0) 177.7 (37.1-775.5) 5.1 (0.8-49.0)
BSREM β 700 5.2 (1.7-9.0) 10.8 (7.0-15.4) 183.5 (38.6-826.6) 4.9 (0.8-47.6)
BSREM β 800 5.2 (1.7-9.0) 10.2 (6.6-14.2) 188.2 (39.7-885.9) 4.8 (0.7-46.5)
BSREM β 900 5.2 (1.7-9.0) 9.8 (6.2-13.8) 191.4 (41.1-927.6) 4.6 (0.7-45.6)
BSREM β 1000 5.2 (1.7-9.0) 9.3 (5.9-13.0) 194.5 (42.0-945.2) 4.5 (0.7-44.5)
BSREM β 1100 5.2 (1.7-9.0) 9.0 (5.7-12.6) 196.2 (42.3-961.3) 4.4 (0.7-43.6)
BSREM β 1200 5.2 (1.7-9.0) 8.7 (5.5-11.7) 199.0 (41.1-1019.1) 4.3 (0.7-42.8)
BSREM β 1300 5.2 (1.7-9.0) 8.4 (5.3-11.7) 201.2 (41.5-1043.1) 4.2 (0.6-42.0)

BSREM: block-sequential regularized expectation maximization; BV: background variability; OSEM: ordered subsets expectation maximization; PSF; point-spread function; SBR: signal-to-background ratio; SNR: signal-to-noise ratio; SUV: standardized uptake value; TOF: time-of-flight.