Table 4.
Joint effects of DRC with SHS exposure and with lung cancer family history
| Controls, n (%) | Cases, n (%) | OR* (95% CI*) | P | ||
|---|---|---|---|---|---|
| DRC | SHS exposure | ||||
| Optimal | No | 45 (19.9) | 10 (7.2) | 1 | |
| Optimal | Yes | 70 (31.0) | 49 (35.3) | 2.68 (1.29–5.56) | 0.0081 |
| Suboptimal | No | 32 (14.2) | 20 (14.4) | 2.94 (1.58–5.48) | 0.0007 |
| Suboptimal | Yes | 79 (35.0) | 60 (43.2) | 3.81 (2.26–6.41) | <0.0001 |
| Family history of lung cancer | |||||
| Optimal | No | 44 (30.2) | 23 (25.8) | 1 | |
| Optimal | Yes | 17 (11.6) | 7 (7.9) | 0.59 (0.24–1.48) | 0.2610 |
| Suboptimal | No | 68 (46.6) | 40 (44.9) | 1.40 (0.86–2.29) | 0.1780 |
| Suboptimal | Yes | 17 (11.6) | 19 (21.4) | 2.49 (1.11–5.60) | 0.0276 |
| Family history of non-smoking-related cancer | |||||
| Optimal | No | 44 (19.6) | 23 (13.7) | 1 | |
| Optimal | Yes | 59 (26.2) | 37 (22.0) | 1.15 (0.46–2.91) | 0.7627 |
| Suboptimal | No | 68 (30.2) | 40 (23.8) | 1.31 (0.78–2.19) | 0.3042 |
| Suboptimal | Yes | 54 (24.0) | 68 (40.5) | 2.88 (1.32–6.28) | 0.0081 |
*
Adjusted for age, gender, ethnicity, dust exposure, and presence of asthma and hay fever and grouped by year of assay using generalized estimating equation model; DRC adjusted for the laboratory variables.