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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: Am J Ophthalmol. 2019 Jan 14;200:242–249. doi: 10.1016/j.ajo.2019.01.004

Table 2.

Clinical investigations of 217 children evaluated for juvenile myasthenia gravis from 1966 through 2015 at Mayo Clinic

No. (%)
Ocular
myasthenia
  N=49		 Generalized
myasthenia
  N=148		 Predominantly
Bulbar *
  N=4		 Predominantly
ocular and
bulbar*
N=16		 Overall
N=217
Tensilon test
 Positive 36 (94.7) 86 (96.6) 3 (100) 8 (80.0) 133 (95.0)
Electromyography
 Positive 19 (47.5) 115 (91.3) 4 (100.0) 16 (100.0) 154 (82.8)
Imaging
 Thymus enlargement 2 (6.3) 13 (9.4) 0 (0.0) 0 (0.0) 15 (7.9)
Antibodies
 Anticholiesterase 20 (60.6) 73 (72.3) 1 (100) 6 (54.6) 100 (68.5)
 Anti-MuSK 0 (0.0) 3 (2.0) 0 (0.0) 2 (12.5) 5 (2.3)
 Anti-striational 0 (0.0) 2 (1.4) 0 (0.0) 0 (0.0) 2 (0.9)
 Seronegative 13 (39.4) 26(25.7) 0 (0.0) 5 (45.5) 44 (30.1)
*

Oropharyngeal muscle involvement