Table 1.
Respiratory values and blood samples during CPR in anesthetized pigs
| Time (min after CPR start) | ||||||||
| Variables | Groups | Baseline | 1 | 6 | 8 | 12 | 21 | 27 |
| Fraction of inspired O2 (%) | Control | 25 (22–29) | 80 (64–97) | 77 (66–88) | 75 (69–81) | 76 (71–82) | 75 (70–80) | 76 (70–82) |
| REBOA-Ib | 25 (22–29) | 53 (36–69) | 65 (53–76) | 74 (68–81) | 71 (65–76) | 71 (65–77) | 67 (60–74) | |
| REBOA-Ic | 24 (20–27) | 75 (59–92) | 70 (59–81) | 70 (64–77) | 68 (62–74) | 71 (65–77) | 67 (61–73) | |
| Arterial PO2 (kPa) | Control | 15.3 (12.5–18.2) | 21.7 (7.8–35.6) | 26.2 (14.5–37.9) | 24.4 (15.9–32.9) | 22.0 (14.6–29.5) | 19.9 (13.1–26.7) | |
| REBOA-Ib | 16.2 (13.3–19.0) | 16.8 (3.1–30.5) | 27.3 (15.6–39.0) | 28.8 (20.1–37.5) | 24.2 (15.9–32.5) | 24.3 (15.6–33.1) | ||
| REBOA-Ic | 14.4 (11.5–17.2) | 20.1 (6.4–33.8) | 29.1 (17.4–40.8) | 25.6 (16.6–34.5) | 30.4 (22.3–38.6) | 22.2 (14.6–29.7) | ||
| Arterial base excess (mmol L−1) | Control | 6.9 (4.6–9.2) | −3.2 (−5.5−−0.9) | −9.5 (−11.8–−7.2) | −13.9 (−16.2–−11.6) | −18.1 (−20.4–−15.8) | −20.2 (−22.5–−17.8) | |
| REBOA-Ib | 7.5 (5.2–9.8) | −1.7 (−4.0–0.6) | −8.0 (−10.3–−5.7) | −10.1 (−12.4–−7.7) | −13.1 (15.7–−10.5) | −16.6 (−19.7–−13.6) | ||
| REBOA-Ic | 6.1 (3.8–8.4) | −5.6 (−7.9–−3.3) | −11.1 (−13.4–−8.8) | −11.9 (−14.3–−9.4) | −14.7 (−17.2–−12.2) | −16.7 (−19.3–−14.2) | ||
| Arterial bicarbonate (mmol L−1) | Control | 30.3 (28.5–32.1) | 22.4 (20.6–24.2) | 17.5 (15.7–19.3) | 14.1 (12.3–15.9) | 10.7 (8.9–12.5) | 9.0 (7.2–10.9) | |
| REBOA-Ib | 30.8 (29.0–32.6) | 23.5 (21.7–25.3) | 18.7 (16.9–20.5) | 17.1 (15.2–18.9) | 14.7 (12.7–16.8) | 11.9 (9.6–14.3) | ||
| REBOA-Ic | 29.7 (27.9–31.5) | 20.6 (18.8–22.4) | 16.2 (14.4–18.0) | 15.7 (13.8–17.6) | 13.5 (11.5–15.5) | 11.9 (9.9–13.9) | ||
Values are displayed as means with a 95% CI. REBOA at heart level (REBOA-Ib, n = 9) or diaphragmatic level (REBOA-Ic, n = 9) and control (no aortic occlusion, n = 9).
CI, confidence interval; CPR, cardiopulmonary resuscitation; REBOA, resuscitative endovascular balloon occlusion of the aorta.