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. 2019 Jun 20;16:26. doi: 10.1186/s12014-019-9245-1

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Differences among pSS phenotypes. Venn diagram of the differentially expressed proteins detected among phenotypes High Focus/Normal Flow, High Focus/Low Flow and Low Focus/Low Flow of pSS disease (a). Heat map showing the differences in terms of protein expression of the 63 common proteins among pSS phenotypes. High Focus/Low Flow and Low Focus/Low Flow patient groups showed the highest level of up-regulated proteins compared to High Focus/Normal Flow group (b)