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. 2019 Jun 21;19:143. doi: 10.1186/s12906-019-2557-x

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Representative histological images of the colon contains fecal pellet, taken from vehicle, SP or FBe-treated normal rats. a = Intact vehicle control (Saline and distilled water administered intact vehicle control rats). b = LP control (LP 3 mg/kg and distilled water administrated constipation control rats). c = Reference (LP 3 mg/kg and SP 5 mg/kg administered rats). d = FBe 300 (LP 3 mg/kg and FBe the highest dosage 300 mg/kg administered rats). e = FBe 200 (LP 3 mg/kg and FBe the middle dosage 200 mg/kg administered rats). f = FBe 100 (LP 3 mg/kg and FBe the lowest dosage 100 mg/kg administered rats). FBe: Triple fermented barley extracts, test material; MM: Colonic mucosa; LU: Lumen; SM: Submucosa: ML: Muscular layer. Arrow indicated surface mucous thicknesses of fecal pellets measured. All alcian blue stain Scale bars = 120 μm