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. 2019 May 31;9(13):3903–3917. doi: 10.7150/thno.31037

Figure 3.

Figure 3

Cathepsin B expression in human inflammatory disease. A: H&E staining of human psoriatic skin tissue obtained from a clinically indicated punch biopsy shows parakeratosis and a dense neutrophil infiltrate. B: Immunofluorescence microscopy revealed cathepsin B expression by T cells (CD3), dendritic cells (Factor XIIIa), B cells (CD20) and NK cells (CD56) comparable to that in tissue from mice with experimental acute cutaneous DTHR (Figure 2). Cathepsin B (red); nuclei (green), CD3/Factor XIIIa/CD20/CD56 (blue); cathepsin B and CD3/Factor XIIIa/CD20/CD56 double-positive cells (pink).