Skip to main content
. 2019 May 31;9(13):3825–3839. doi: 10.7150/thno.33958

Figure 5.

Figure 5

Cellular uptake and in vitro cytotoxicity of DOX@pPGNCs. (A-D) Intracellular Au content in MCF-7 (A), MCF-7/ADR (B), HepG2 (C) and HepG2/ADM cells (D) after treatment with DOX@PGNCs or DOX@pPGNCs at Au concentration of 10 µg/mL for 12 h at pH 7.4 or 6.5, respectively. (E-F) in vitro cytotoxicity against MCF-7 (E) or MCF-7/ADR cells (F) after treatment with PBS, free DOX, GNCs, PGNCs, pPGNCs, DOX@PGNCs or DOX@pPGNCs at DOX concentration of 1.2 μg/mL and Au concentration of 10 μg/mL at pH 7.4 or 6.5 for 24 h, respectively, followed with or without 808 nm laser irradiation (0.7 W/cm2) for 5 min and incubation for another 4 h. The data are presented as the mean ± SD (n = 3).