Figure 9.

In vivo anticancer activity of DOX@pPGNCs. (A) Tumor growth curves of MCF-7/ADR tumor-bearing nude mice after intravenous injection of various formulations at the dosage of 20 mg/kg Au and 2.4 mg/kg DOX, followed with 808 nm laser irradiation (0.7 W/cm²) for 5 min at the tumor sites once every other day. (B) Photos of tumors after treatment. (C) Tumor weight after treatment. (D) Body weight change of MCF-7/ADR tumor-bearing nude mice after treatment as above. The data are presented as the mean ± SD (n = 5 mice for each group). **P<0.01, ***P<0.001.